IDENTIFICATION OF A NOVEL HETEROZYGOUS SPTB MUTATION BY WHOLE GENOME SEQUENCING IN A CHINESE PATIENT WITH HEREDITARY SPHEROCYTOSIS AND ATRIAL SEPTAL DEFECT: A CASE REPORT

Abstract Background Hereditary spherocytosis (HS) is a common inherited red blood cell membrane disorder characterized by an abnormal increase of spherocytes in peripheral blood.SPTB gene mutation is one of the most common causes of HS; however, few cases of HS resulting from SPTB mutation in the Chinese population have been reported so far.Case pr

Citrus melanose consists of a series of ngetikin plant diseases caused by the fungal species of the genus Diaporthe.It has been reported with over 30 Diaporthe species on citrus, including several important fungal pathogens, endophytes, saprophytes, and also latent fungal pathogens with an endophytic/saprophytic lifestyle.Among them, the disease sy

Zimbabwe, located in Southern Africa, faces a significant public health challenge due to schistosomiasis.We investigated this issue with emphasis on risk prediction of schistosomiasis for the entire population.To this end, we reviewed available data on schistosomiasis in Zimbabwe from a literature search covering the 1980-2022 period considerin